Botox transient treatment of tinnitus
due to stapedius myoclonus: Case report
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Hai-Bin Liua, Jing-Ping Fana, Shun-Zhang Lin
, a,
, Shu-Wei Zhao
, a,
and Zheng Lina
a Department of Otolaryngology-Head & Neck Surgery, ChangZheng Hospital, Second Military Medical University, Fengyang Road 415, Huangpu District, Shanghai, China
Received 21 October 2009;
revised 23 July
2010;
accepted 31 July
2010.
Available online 25 August
2010.
Abstract
Object
To explore the feasibility of using botulinum toxin type A (BTXA) to treat
tinnitus
due to stapedius myoclonus.
Method
A piece of gelfoam containing BTXA (25 U/ml) was placed, through a perforation in tympanic membrane, into the middle ear cavity of a patient suffering from
tinnitus
due to stapedius myoclonus.
Results
The
tinnitus
disappeared on the second day after the BTXA treatment. The patient was free of symptoms during a 3-month follow-up period.
Tinnitus
reappeared at 4 months, and disappeared after second BTXA local treatment.
Conclusion
Local BTXA treatment may be considered as a treatment for
tinnitus
caused by stapedius myoclonus.
Keywords: Botulinum toxin type A;
Tinnitus
; Stapedius myoclonus

Corresponding authors. Tel.: +86 021 81885962; fax: +86 021 63520020.
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