Authors: Coelho Claudia Barros, Tyler Richard, Hamsen M.
Source
Department of Otolaryngology, Head and Neck Surgery, The University of Iowa, Iowa City, IA, USA. claudia-coelho@uiowa.edu
Fuente de la imagen: www.yingyangperu.com
Abstract
Zinc
is an essential trace element present in all organs, tissues, fluids,
and secretions of the body and it is widely distributed in the central
nervous system, including the auditory pathway in synapses of the VIII
nerve and in the cochlea.
Zinc is an essential component of Cu/Zn superoxide dismutase (SOD) and in certain enzymes and it is important for proper function of the immune system.
Three possible mechanisms have linked zinc to tinnitus; cochlear Cu/Zn SOD activity, synaptic transmission, and depression.
Evidences in the literature suggest prevalence rates of zinc deficiency in individuals with tinnitus from 2 to 69%, affecting elderly individuals more frequently.
Four among five small studies indicate that administration of zinc has a beneficial effect on tinnitus but these results still have to be confirmed in clinical trials with larger samples using a cross-over design, validated tinnitus handicap questionnaires, measurements of tinnitus magnitude, and accessing the coexistence of other symptoms such as depression, phonophobia, and hyperacusis.
Fuente: http://www.ncbi.nlm.nih.gov/pubmed/17956792
Zinc is an essential component of Cu/Zn superoxide dismutase (SOD) and in certain enzymes and it is important for proper function of the immune system.
Three possible mechanisms have linked zinc to tinnitus; cochlear Cu/Zn SOD activity, synaptic transmission, and depression.
Evidences in the literature suggest prevalence rates of zinc deficiency in individuals with tinnitus from 2 to 69%, affecting elderly individuals more frequently.
Four among five small studies indicate that administration of zinc has a beneficial effect on tinnitus but these results still have to be confirmed in clinical trials with larger samples using a cross-over design, validated tinnitus handicap questionnaires, measurements of tinnitus magnitude, and accessing the coexistence of other symptoms such as depression, phonophobia, and hyperacusis.
Fuente: http://www.ncbi.nlm.nih.gov/pubmed/17956792
Prog Brain Res.2007;166:279-85.
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