viernes, 5 de febrero de 2010

tailor-made notched music reduces tinnitus

Listening to tailor-made notched music reduces tinnitus loudness and tinnitus-related auditory cortex activity

1. Hidehiko Okamotoa,1,
2. Henning Strackea,1,
3. Wolfgang Stollb,2, and
4. Christo Panteva,3

+ Author Affiliations

aInstitute for Biomagnetism and Biosignalanalysis, Westfalian Wilhelms-University, Malmedyweg 15, Muenster, Germany; and
bDepartment of Otorhinolaryngology, Head and Neck Surgery, Muenster University Hospital, Kardinal-von-Galen-Ring 10, 48149 Muenster, Germany

Maladaptive auditory cortex reorganization may contribute to the generation and maintenance of tinnitus.

Because cortical organization can be modified by behavioral training, we attempted to reduce tinnitus loudness by exposing chronic tinnitus patients to self-chosen, enjoyable music, which was modified (“notched”) to contain no energy in the frequency range surrounding the individual tinnitus frequency.

After 12 months of regular listening, the target patient group (n = 8) showed significantly reduced subjective tinnitus loudness and concomitantly exhibited reduced evoked activity in auditory cortex areas corresponding to the tinnitus frequency compared to patients who had received an analogous placebo notched music treatment (n = 8).

These findings indicate that tinnitus loudness can be significantly diminished by an enjoyable, low-cost, custom-tailored notched music treatment, potentially via reversing maladaptive auditory cortex reorganization.

Fuente: PNAS, Proceedings of the National Academy of Sciences of the United States of America. Edited by Michael M. Merzenich, University of California at San Francisco, San Francisco, CA, and approved December 3, 2009 (received for review September 30, 2009),1H.O. and H.S.contributed equally to this work.

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