sábado, 30 de junio de 2012

Assessment of cochlear and auditory pathways in patients with migraine


  • Sherifa Ahmad Hamed, MDa, Corresponding author contact information, E-mail the corresponding author,
  • Ahmed Hamdy Youssef, MDa,
  • Amal Mohammad Elattar, MDb
  • a Department of Neurology and Psychiatry, Assiut University Hospital, Assiut, Egypt
  • b Department of Ear, Nose and Throat, Audiology Unit, Assiut University Hospital, Assiut, Egypt



In this study, we aimed to determine the function of the cochlea and peripheral and central auditory pathways with migraine.

Materials and methods

Fifty-eight patients with migraine and 40 healthy subjects were assessed using routine diagnostic audiometry along with transient evoked otoacoustic emissions (TOAEs), distortion product otoacoustic emissions (DPOAEs), and auditory brainstem response (ABR) at high and low repetition rate frequencies.


Nearly two thirds of patients with migraine had one or more abnormalities in electrophysiological testing. Compared with control subjects, patients reported significant lowering of TOAEs amplitude at frequencies of 1 kHz (right: P = .0003; left: P = .002), 3 kHz (right: P = .025), and 4 kHz (right: P = .019); prolonged wave III latency (right: P = .009); and I-V interpeak latency (IPL) (left: P = .024) at high repetition rate frequencies. Significant correlations were identified between age, duration of illness and frequency of migraine and TOAEs total response and at amplitude of 4 kHz, amplitudes of DPOAEs at 1, 1.5, 2, 3, and 5 kHz and I, III and wave latencies and I-V IPL of ABR at high rate frequencies.


These data suggest that subclinical changes in cochlear function and auditory pathways are associated with chronic migraine. It is possible that migraine could be accompanied by compromise of blood supply of auditory system.

Volume 33, Issue 4, July–August 2012, Pages 385–394
Fuente de la imagen:  http://www.google.com.ar/imgres?hl=es&biw=1280&bih=612&tbm=isch&tbnid=D0qQux4gGQmZ2M:&imgrefurl=http://thenpmom.wordpress.com/2012/04/24/migraine-headaches-just-another-headache/&docid=4VMUYEPgoOMXMM&imgurl=http://thenpmom.files.wordpress.com/2012/04/migrainesufferer.jpg&w=900&h=542&ei=eXPvT57kGYyK8QTnp92jDQ&zoom=1

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