viernes, 18 de febrero de 2011

Hiperacusia: Sección mecanismos fisopatologicos.

Brain activation in patients with idiopathic hyperacusisnext term

Juen-Haur Hwang MDa, Pao-Hsuan Choub, Chang-Wei Wu PhDc, Jyh-Horng Chen PhDc and Tien-Chen Liu MD, PhDd, Corresponding Author Contact Information, E-mail The Corresponding Author
aDepartment of Otolaryngology, Buddhist Dalin Tzu Chi General Hospital, Chiayi, and School of Medicine, Tzu Chi University, Hualien, Taiwan
bDepartment of Otolaryngology, Taichung Veterans General Hospital, Taichung
cInterdisciplinary MRI/MRS Laboratory, Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan
dDepartment of Otolaryngology, National Taiwan University Hospital, Taipei, Taiwan
Received 21 July 2008. 
Available online 6 March 2009.


The neural network associated with idiopathic previous termhyperacusisnext term is still not well known.

We studied the brain activation of 3 middle-aged patients with mild to moderate previous termhyperacusisnext term by functional magnetic resonance imaging while they were listening to white noise binaurally.

In addition to the temporal lobes, in all patients, sound elicited activation in the frontal lobes (superior, middle, or inferior frontal gyri) and occipital lobes (precuneus, cuneus, superior occipital gyrus, lingual gyrus, or fusiform gyrus).

The parahippocampus was activated in 2 of 3 patients.

Furthermore, the precentral and postcentral gyri, superior and inferior parietal lobules, thalamus, midbrain, claustrum, insula, posterior cingulated gyrus, and orbital and rectal gyrus were also activated in one patient.

The neural network associated with idiopathic previous termhyperacusisnext term might be associated with the frontal lobes and parahippocampus.

Corresponding Author Contact InformationCorresponding author. Department of Otolaryngology, National Taiwan University Hospital, No 7, Chung-Shan S. Road, Taipei, Taiwan. Tel.: +886 2 23123456x5896; fax: +886 2 23410905.

Fuente: American Journal of Otolaryngology
Volume 30, Issue 6, November-December 2009, Pages 432-434

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